Jingxia Li Selected Research

X-Linked Inhibitor of Apoptosis Protein

12/2019	The RING domain in the anti-apoptotic protein XIAP stabilizes c-Myc protein and preserves anchorage-independent growth of bladder cancer cells.
1/2018	XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability.
1/2017	XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell.
8/2014	X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis.
7/2013	X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis.
10/2012	The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP.
4/2012	RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility.
5/2011	X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton.

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Jingxia Li Research Topics

Disease

63	Neoplasms (Cancer) 01/2022 - 10/2002
31	Urinary Bladder Neoplasms (Bladder Cancer) 12/2021 - 10/2012
20	Carcinogenesis 01/2017 - 05/2002
8	Lung Neoplasms (Lung Cancer) 01/2021 - 08/2006
7	Neoplasm Metastasis (Metastasis) 12/2019 - 04/2012
6	Inflammation (Inflammations) 06/2011 - 11/2002
5	Pneumonia (Pneumonitis) 10/2016 - 02/2009
3	Hypoxia (Hypoxemia) 10/2012 - 01/2004
3	Skin Neoplasms (Skin Cancer) 01/2008 - 04/2006
2	Carcinoma (Carcinomatosis) 06/2017 - 01/2015
2	Esophageal Neoplasms (Esophageal Cancer) 01/2015 - 06/2005
2	Colonic Neoplasms (Colon Cancer) 03/2014 - 01/2006
2	Leukemia 02/2014 - 09/2013
1	Uterine Cervicitis (Cervicitis) 01/2022
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022
1	Infections 01/2022
1	Necrosis 01/2022
1	Papillomavirus Infections 01/2022
1	Liver Neoplasms (Liver Cancer) 01/2021
1	Endometrioid Carcinoma 01/2020
1	Glioma (Gliomas) 01/2020
1	Communicable Diseases (Infectious Diseases) 05/2019
1	Lymphatic Metastasis 01/2019
1	Cholangiocarcinoma 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 08/2018
1	Endometrial Neoplasms (Endometrial Cancer) 08/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2018
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 10/2017

Drug/Important Bio-Agent (IBA)

21	Proteins (Proteins, Gene)FDA Link 12/2021 - 08/2005
11	isorhapontigeninIBA 11/2021 - 10/2012
11	Cyclin D1IBA 01/2020 - 07/2006
10	arseniteIBA 09/2013 - 10/2005
9	CarcinogensIBA 07/2016 - 05/2004
8	X-Linked Inhibitor of Apoptosis ProteinIBA 12/2019 - 05/2011
8	Transcription Factors (Transcription Factor)IBA 09/2014 - 10/2002
8	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2007 - 10/2002
7	Biological ProductsIBA 01/2020 - 05/2011
7	NickelIBA 10/2016 - 10/2002
6	Small Interfering RNA (siRNA)IBA 12/2019 - 11/2006
6	Messenger RNA (mRNA)IBA 12/2019 - 09/2014
5	NF-kappa B (NF-kB)IBA 01/2007 - 10/2002
4	cheliensisin AIBA 11/2018 - 09/2013
4	LactonesIBA 11/2018 - 09/2013
4	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 06/2011 - 07/2006
4	Epoxy Compounds (Epoxides)IBA 01/2007 - 04/2004
4	Benzo(a)pyreneIBA 01/2007 - 05/2004
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2015
3	MicroRNAs (MicroRNA)IBA 01/2020 - 01/2017
3	Matrix Metalloproteinases (MMPs)IBA 01/2020 - 11/2017
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019 - 08/2005
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2015 - 03/2006
3	CytokinesIBA 01/2015 - 11/2002
3	rho-Specific Guanine Nucleotide Dissociation InhibitorsIBA 04/2012 - 05/2011
2	Long Noncoding RNAIBA 09/2020 - 08/2018
2	ChlA-FIBA 01/2020 - 11/2018
2	Pharmaceutical PreparationsIBA 01/2019 - 01/2016
2	Phosphotransferases (Kinase)IBA 01/2019 - 10/2018
2	Leucine-Rich Repeat ProteinsIBA 01/2019 - 10/2018
2	NucleolinIBA 01/2018 - 02/2015
2	NitrosaminesIBA 01/2018 - 07/2016
2	StilbenesIBA 07/2016 - 08/2013
2	Therapeutic UsesIBA 05/2014 - 02/2014
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 09/2013 - 08/2010
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 07/2013 - 01/2012
2	EnzymesIBA 06/2011 - 09/2007
2	ArsenicIBA 02/2009 - 04/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2006 - 01/2006
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 08/2005 - 01/2004
1	Interleukin-4 (Interleukin 4)IBA 01/2022
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	NeuropeptidesIBA 01/2022
1	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 01/2022
1	VimentinIBA 11/2021
1	Apoptosis Regulatory ProteinsIBA 12/2019
1	SeleniumIBA 11/2019
1	TubulinIBA 11/2019
1	Competitive Endogenous RNAIBA 06/2019
1	C-Reactive ProteinIBA 05/2019
1	Immune Checkpoint InhibitorsIBA 03/2019
1	Programmed Cell Death 1 ReceptorIBA 03/2019
1	LigandsIBA 03/2019
1	B7-H1 AntigenIBA 03/2019
1	Biocompatible Materials (Biomaterials)IBA 01/2019
1	PerforinIBA 01/2019
1	Tissue Inhibitor of Metalloproteinase-2IBA 01/2019
1	ChitosanIBA 01/2019
1	Inhibitor of Apoptosis ProteinsIBA 11/2017
1	benzothiazoleIBA 10/2017
1	Cadherins (E-Cadherin)IBA 10/2017
1	ButylhydroxybutylnitrosamineIBA 06/2017
1	E2F1 Transcription FactorIBA 01/2017
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2017
1	Antineoplastic Agents (Antineoplastics)IBA 01/2017
1	Beclin-1IBA 10/2016

Therapy/Procedure

11	Therapeutics 01/2021 - 03/2014
3	Immunotherapy 01/2021 - 01/2019
2	Cell- and Tissue-Based Therapy (Cell Therapy) 11/2019 - 01/2019
2	Radiotherapy 01/2019 - 01/2015
1	Liver Transplantation 01/2019
1	Drug Therapy (Chemotherapy) 01/2019